{"id":11444,"date":"2025-10-03T20:40:29","date_gmt":"2025-10-03T20:40:29","guid":{"rendered":"https:\/\/andromedichyperthermia.com\/hyperthermia-quality-of-life-qol\/"},"modified":"2025-10-04T15:34:01","modified_gmt":"2025-10-04T15:34:01","slug":"%e6%b8%a9%e7%86%b1%e7%99%82%e6%b3%95%ef%bc%88ht%ef%bc%89%e3%81%8c%e7%94%9f%e6%b4%bb%e3%81%ae%e8%b3%aa%ef%bc%88qol%ef%bc%89%e3%81%ab%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf","status":"publish","type":"post","link":"https:\/\/andromedichyperthermia.com\/ja\/%e6%b8%a9%e7%86%b1%e7%99%82%e6%b3%95%ef%bc%88ht%ef%bc%89%e3%81%8c%e7%94%9f%e6%b4%bb%e3%81%ae%e8%b3%aa%ef%bc%88qol%ef%bc%89%e3%81%ab%e4%b8%8e%e3%81%88%e3%82%8b%e5%bd%b1%e9%9f%bf\/","title":{"rendered":"\u6e29\u71b1\u7642\u6cd5\uff08HT\uff09\u304c\u751f\u6d3b\u306e\u8cea\uff08QoL\uff09\u306b\u4e0e\u3048\u308b\u5f71\u97ff\uff1a\u75bc\u75db\u7de9\u548c\u3001\u75b2\u52b4\u8efd\u6e1b\u3001\u304a\u3088\u3073\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u514d\u75ab\u5b66\u7684\u5229\u76ca"},"content":{"rendered":"<p><script type=\"application\/ld+json\">\n    {\n      \"@context\": \"https:\/\/schema.org\",\n      \"@type\": \"MedicalScholarlyArticle\",\n      \"headline\": \"\u6e29\u71b1\u7642\u6cd5\uff08HT\uff09\u304c\u751f\u6d3b\u306e\u8cea\uff08QoL\uff09\u306b\u4e0e\u3048\u308b\u5f71\u97ff\uff1a\u75bc\u75db\u7de9\u548c\u3001\u75b2\u52b4\u8efd\u6e1b\u3001\u304a\u3088\u3073\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u514d\u75ab\u5b66\u7684\u5229\u76ca\",\n      \"author\": {\n        \"@type\": \"Person\",\n        \"name\": \"Gologan Cristian, M.Sc.\",\n        \"jobTitle\": \"CEO\",\n        \"affiliation\": {\n          \"@type\": \"MedicalOrganization\",\n          \"name\": \"\u30a2\u30f3\u30c9\u30ed\u30e1\u30c7\u30a3\u30c3\u30af\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2\u30bb\u30f3\u30bf\u30fc\"\n        }\n      },\n      \"keywords\": \"\u6e29\u71b1\u7642\u6cd5, \u816b\u760d\u5b66, \u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13, QoL, \u75bc\u75db, E-E-A-T\"\n      \/*... FAQPage\u30b9\u30ad\u30fc\u30de\u306f\u3001\u3088\u304f\u3042\u308b\u8cea\u554f\u30bb\u30af\u30b7\u30e7\u30f3\u7528\u306b\u5225\u9014\u8ffd\u52a0\u3055\u308c\u307e\u3059 *\/\n    }\n<\/script><\/p>\n<article>\n<header>\n<div class=\"author-info\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6a29\u5a01\u3068\u5c02\u9580\u6027 (EEAT): <\/span><\/span><\/strong><br \/>\n<strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8457\u8005: <\/span><\/span><a href=\"https:\/\/andromedichyperthermia.com\/hyperthermia-doctor-veronica-iatan\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Dr. Veronica Iatan<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> , MD, \u304a\u3088\u3073 <\/span><\/span><a href=\"https:\/\/andromedichyperthermia.com\/cristian-gologan\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">Cristian Gologan M.Sc<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> , \u30a2\u30f3\u30c9\u30ed\u30e1\u30c7\u30a3\u30c3\u30af\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2<\/span><\/span><\/strong><\/div>\n<h1><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6e29\u71b1\u7642\u6cd5\uff08HT\uff09\u304c\u751f\u6d3b\u306e\u8cea\uff08QoL\uff09\u306b\u4e0e\u3048\u308b\u5f71\u97ff\uff1a\u75bc\u75db\u7de9\u548c\u3001\u75b2\u52b4\u8efd\u6e1b\u3001\u304a\u3088\u3073\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u514d\u75ab\u5b66\u7684\u5229\u76ca<\/span><\/span><\/h1>\n<\/header>\n<section><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u73fe\u4ee3\u306e\u816b\u760d\u5b66\u306b\u304a\u3044\u3066\u3001\u304c\u3093\u6cbb\u7642\u306f<a href=\"https:\/\/andromedichyperthermia.com\/hyperthermia-survival-cancer-patients\/\"> \u751f\u5b58\u7387 (OS\/DFS)<\/a>\u3068 <\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u751f\u6d3b\u306e\u8cea (QoL)<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u306e\u6700\u9069\u306a\u30d0\u30e9\u30f3\u30b9\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002\u6e29\u71b1\u7642\u6cd5\uff08HT\uff09\u306f\u3001\u4e3b\u8981\u306a\u81e8\u5e8a\u8a66\u9a13\uff08 <\/span><\/span><a href=\"https:\/\/andromedichyperthermia.com\/oncologic-hyperthermia-phase-3-trials\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7b2cIII\u76f8RCT<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff09\u3092\u901a\u3058\u3066\u8a3c\u660e\u3055\u308c\u3066\u3044\u308b\u3001\u75c7\u72b6\u7ba1\u7406\u3001\u4e00\u822c\u7684\u306a\u6a5f\u80fd\u72b6\u614b\u3001\u304a\u3088\u3073\u512a\u308c\u305f\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306a\u3069\u591a\u5c90\u306b\u308f\u305f\u308b\u30ec\u30d9\u30eb\u3067QoL\u3092\u6539\u5584\u3059\u308b\u30e6\u30cb\u30fc\u30af\u306a\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/span><\/span><\/section>\n<hr \/>\n<section>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">1. \u4e3b\u8981\u306a\u7de9\u548c\u30b1\u30a2\u306e\u5229\u76ca\uff1a\u75bc\u75db\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\uff08\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13\u304b\u3089\u306eA1\u30ec\u30d9\u30eb\u306e\u8a3c\u62e0\uff09<\/span><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8ee2\u79fb\u6027\u9aa8\u75db\u306fQoL\u3092\u4f4e\u4e0b\u3055\u305b\u307e\u3059\u3002\u5c40\u6240\u6e29\u71b1\u7642\u6cd5\uff08RF-Hyperthermia\uff09\u306f\u3001\u653e\u5c04\u7dda\u7642\u6cd5\uff08RT\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001Chi MS\u3089\u304c\u767a\u8868\u3057\u305f \u7b2cIII\u76f8 \u8a66\u9a13\uff082017\uff09\u306b\u3088\u308b\u3068\u3001\u512a\u308c\u305f\u7de9\u548c\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u63d0\u4f9b\u3057\u307e\u3059[1]\uff1a<\/span><\/span><\/p>\n<table style=\"width: 100%; border-collapse: collapse;\" border=\"1\">\n<thead>\n<tr style=\"background-color: #f2f2f2;\">\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">QoL\u6307\u6a19\/\u75bc\u75db\u6539\u5584<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">RT\u5358\u72ec\u7642\u6cd5<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">RT + \u6e29\u71b1\u7642\u6cd5 (HT)<\/span><\/span><\/th>\n<th>QoL\u3078\u306e\u5f71\u97ff<\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3\u30f6\u6708\u6642\u70b9\u3067\u306e\u5b8c\u5168\u594f\u52b9\u7387 (CR)<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> (\u75bc\u75db\u30b9\u30b3\u30a2\u30bc\u30ed)<\/span><\/span><\/td>\n<td>7,1 %<\/td>\n<td>37,9 %<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5168\u75bc\u75db\u6392\u9664\u306e\u53ef\u80fd\u6027\u304c 533%\u5897\u52a0\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75bc\u75db\u7de9\u548c\u306e\u6301\u7d9a\u671f\u9593<\/span><\/span><\/strong><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u592e\u5024: 55\u65e5\/7.9\u9031<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u592e\u5024: 24\u9031\u3067\u672a\u5230\u9054<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7de9\u548c\u671f\u9593\u304c 3\u500d\u306b\u306a\u308a\u3001\u93ae\u75db\u5264\u3078\u306e\u4f9d\u5b58\u3092\u6e1b\u3089\u3059\u3002<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2024\u5e74\u3001Sahinbas\u3089\u306f\u3001RT\u306b\u52a0\u3048\u3066WBHT wIRA\u6e29\u71b1\u7642\u6cd5\u3092\u7528\u3044\u305f\u3001\u4e3b\u306b\u4e73\u304c\u3093\u3068\u524d\u7acb\u817a\u304c\u3093\u306b\u3088\u308b\u9aa8\u8ee2\u79fb\u75db\u306b\u95a2\u3059\u308b\u7b2cIII\u76f8\u7814\u7a76\u3092\u767a\u8868\u3057\u307e\u3057\u305f\u3002[2]<\/span><\/span><\/p>\n<p><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3053\u306e\u7814\u7a76\u306b\u57fa\u3065\u304f\u3068\u3001\u653e\u5c04\u7dda\u7642\u6cd5\uff08RT\uff09\u5358\u72ec\u7fa4\u304c\u6700\u3082\u5f37\u3044\u75db\u307f\u3092\u5448\u3057\u307e\u3057\u305f\u3002\u7814\u7a76\u306f\u3001\u6700\u521d\u306e\u767b\u9332\u304b\u30895\u5e74\u5f8c\uff082016\u5e744\u6708\uff5e2021\u5e742\u6708\uff09\u306b\u5408\u8a0861\u540d\u306e\u60a3\u8005\u3092\u767b\u9332\u3057\u305f\u5f8c\u3001\u5b8c\u4e86\u3057\u307e\u3057\u305f\u3002\u6700\u7d42\u7684\u306b\u3001RT + WBH\u7fa4\u306eCR\u7387\u306f\u3001RT\u5358\u72ec\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u3001\u6cbb\u7642\u5f8c2\u30f6\u6708\u4ee5\u5185\u306b\u305d\u308c\u305e\u308c47.4%\u5bfe5.3%\u3068\u6700\u3082\u6709\u610f\u306a\u5dee\u3092\u793a\u3057\u307e\u3057\u305f\uff08P\u5024 &lt; 0.05\uff09\u3002RT + WBH\u306e\u5b8c\u5168\u75bc\u75db\u7de9\u548c\u307e\u3067\u306e\u6642\u9593\u306f10\u65e5\u9593\u3067\u3057\u305f\u304c\u3001RT\u5358\u72ec\u7fa4\u3067\u306f\u30a8\u30f3\u30c9\u30dd\u30a4\u30f3\u30c8\u306b\u5230\u9054\u3057\u307e\u305b\u3093\u3067\u3057\u305f\u3002RT\u7fa4\u306e\u60a3\u8005\u306e\u534a\u6570\u3067\u6cbb\u7642\u5f8c4\u9031\u9593\u4ee5\u5185\u306b\u75bc\u75db\u306e\u9032\u884c\u307e\u305f\u306f\u75be\u60a3\u306e\u5b89\u5b9a\u6027\u304c\u89b3\u5bdf\u3055\u308c\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001RT + WBHT\u60a3\u8005\u3067\u306f\u6cbb\u7642\u5f8c2\u30f6\u6708\u4ee5\u5185\u306b\u3053\u306e\u30b9\u30b3\u30a2\u306f\u30bc\u30ed\u306b\u8fd1\u304f\u306a\u308a\u307e\u3057\u305f\u3002<\/span><\/span><\/span><\/p>\n<p><strong class=\"sub-title\"><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7d50\u8ad6\uff1a\u00a0<\/span><\/span><\/span><\/strong><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> WBH\u3068RT\u306e\u4f75\u7528\u306f\u3001\u8ee2\u79fb\u6027\u9aa8\u75c5\u5909\u3092\u6709\u3059\u308b\u60a3\u8005\u306b\u304a\u3044\u3066\u3001RT\u5358\u72ec\u3068\u6bd4\u8f03\u3057\u3066\u75bc\u75db\u7de9\u548c\u306e\u6709\u610f\u306a\u5897\u52a0\u3068\u77ed\u3044\u53cd\u5fdc\u6642\u9593\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<table style=\"width: 100%; border-collapse: collapse;\" border=\"1\">\n<thead>\n<tr style=\"background-color: #f2f2f2;\">\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">QoL\u6307\u6a19\/\u75bc\u75db\u6539\u5584<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">RT\u5358\u72ec\u7642\u6cd5<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">RT + \u6e29\u71b1\u7642\u6cd5 (WBHT wIRA)<\/span><\/span><\/th>\n<th><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">QoL\u3078\u306e\u5f71\u97ff<\/span><\/span><\/th>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2\u30f6\u6708\u3067\u306e\u5b8c\u5168\u594f\u52b9\u7387 (CR)<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> (\u75bc\u75db\u30b9\u30b3\u30a2\u30bc\u30ed)<\/span><\/span><\/td>\n<td>5,3 %<\/td>\n<td>47,4 %<\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">* <\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">894%\u5897\u52a0<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> * \u5168\u75bc\u75db\u6392\u9664\u306e\u53ef\u80fd\u6027\u3002<\/span><\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span dir=\"auto\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b8c\u5168\u75bc\u75db\u7de9\u548c\u307e\u3067\u306e\u6642\u9593<\/span><\/span><\/span><\/strong><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672a\u5230\u9054<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">10\u65e5\u9593<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8457\u3057\u304f\u8fc5\u901f\u306a\u5229\u76ca<\/span><\/span><\/strong><\/span><\/td>\n<\/tr>\n<tr>\n<td><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75bc\u75db\u7de9\u548c\u306e\u6301\u7d9a\u671f\u9593\u00a0<\/span><\/span><\/strong><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u592e\u5024: 28\u65e5\/4\u9031\uff08\u534a\u6570\u306e\u60a3\u8005\u3067\uff09<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u4e2d\u592e\u5024: 24\u9031\u3067\u672a\u5230\u9054<\/span><\/span><\/td>\n<td><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7de9\u548c\u671f\u9593\u304c * <\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">6\u500d\u306b\u5897\u52a0\u3057<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> *, \u93ae\u75db\u5264\u3078\u306e\u4f9d\u5b58\u3092\u6e1b\u3089\u3059\u3002<\/span><\/span><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<hr \/>\n<section>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">2. \u6a5f\u80fd\u72b6\u614b\u306e\u6539\u5584\u3068\u75b2\u52b4\u306e\u8efd\u6e1b<\/span><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HT\u306eQoL\u3078\u306e\u5229\u76ca\u306f\u3001\u6a19\u6e96\u5316\u3055\u308c\u305f\u8cea\u554f\u7968\uff08EORTC QLQ-C30\uff09\u3092\u901a\u3058\u3066\u76f4\u63a5\u6e2c\u5b9a\u53ef\u80fd\u3067\u3042\u308a\u3001\u4e00\u822c\u72b6\u614b\uff08\u8eab\u4f53\u6a5f\u80fd\u3001\u75b2\u52b4\u3001\u4e0d\u5b89\uff09\u306e\u6539\u5584\u3092\u793a\u3057\u3066\u3044\u307e\u3059\uff1a<\/span><\/span><\/p>\n<ul>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">QoL\u306e\u8457\u3057\u3044\u6539\u5584\uff08\u5909\u8abfRF\u6e29\u71b1\u7642\u6cd5 mHT\uff09\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u5b50\u5bae\u9838\u304c\u3093\uff08LACC\uff09\u306b\u304a\u3051\u308b\u5909\u8abfRF\u6e29\u71b1\u7642\u6cd5\uff08mEHT\uff09\u306e\u7121\u4f5c\u70ba\u5316\u81e8\u5e8a\u8a66\u9a13\u3067\u306f\u3001*\u9577\u671f\u7684\u306aQoL\u30b9\u30b3\u30a2\u306e\u8457\u3057\u3044\u6539\u5584*\u304c\u5831\u544a\u3055\u308c\u3066\u304a\u308a\u3001\u60a3\u8005\u306f*\u8eab\u4f53\u7684\u304a\u3088\u3073\u611f\u60c5\u7684\u6a5f\u80fd*\u30b9\u30b1\u30fc\u30eb\u3067\u3088\u308a\u826f\u3044\u30b9\u30b3\u30a2\u3092\u5831\u544a\u3057\u307e\u3057\u305f\u3002[3]<\/span><\/span><\/li>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u75b2\u52b4\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3068\u514d\u75ab\u8abf\u7bc0\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u5168\u8eab\u6e29\u71b1\u7642\u6cd5\uff08WBHT\uff09\u304a\u3088\u3073\u4e00\u822c\u7684\u306aHT\u306f\u3001\u708e\u75c7\u6027\u30b5\u30a4\u30c8\u30ab\u30a4\u30f3\uff08IL-6\u3001TNF-\u30a2\u30eb\u30d5\u30a1\uff09\u3092\u8abf\u7bc0\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u3001*\u6162\u6027\u75b2\u52b4\uff08CRF\uff09*\u306b\u30dd\u30b8\u30c6\u30a3\u30d6\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u3059\u3002HT\u306f\u307e\u305f\u3001*\u8eab\u4f53\u7684\u304a\u3088\u3073\u611f\u60c5\u7684\u6a5f\u80fd*\u306e\u30b9\u30b1\u30fc\u30eb\u3067\u306e\u30b9\u30b3\u30a2\u3092\u9577\u671f\u7684\u306b\u7dad\u6301\u304a\u3088\u3073\u6539\u5584\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002[4]<\/span><\/span><\/li>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8fc5\u901f\u306a\u611f\u60c5\u7684\u56de\u5fa9\uff08HIPEC\uff09\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> HT\uff08HIPEC\uff09\u3092\u542b\u3080\u4e3b\u8981\u306a\u5916\u79d1\u7684\u51e6\u7f6e\u306e\u5f8c\u3001\u611f\u60c5\u7684\u306aQoL\u306f*\u6025\u901f\u306b\u6539\u5584*\u3059\u308b\u50be\u5411\u304c\u3042\u308a\u3001\u3057\u3070\u3057\u3070\u624b\u8853\u5f8c *3\u30f6\u6708*\u3068\u3044\u3046\u65e9\u3044\u6642\u671f\u304b\u3089\u59cb\u307e\u308a\u3001\u30d9\u30fc\u30b9\u30e9\u30a4\u30f3\u30ec\u30d9\u30eb\u3092\u8d85\u3048\u308b\u3053\u3068\u3082\u3042\u308a\u307e\u3059\u3002[5]<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<hr \/>\n<section>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">3. \u9577\u671f\u7684\u306aQoL\u5229\u76ca\u306e\u78ba\u7acb<\/span><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5b9f\u81e8\u5e8a\u30c7\u30fc\u30bf\u3068\u9032\u884c\u304c\u3093\u306b\u304a\u3051\u308b\u81e8\u5e8a\u8a66\u9a13\u306f\u3001\u9577\u671f\u7684\u306aQoL\u306e\u5b89\u5b9a\u5316\u3068\u6539\u5584\u306b\u304a\u3051\u308b\u6e29\u71b1\u7642\u6cd5\u306e\u5f79\u5272\u3092\u5f37\u5316\u3057\u3066\u3044\u307e\u3059\uff1a<\/span><\/span><\/p>\n<ul>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">12\u30f6\u6708\u6642\u70b9\u3067\u306e\u6cbb\u7652\u7684\u52b9\u679c\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u6cbb\u7652\u7684\u610f\u56f3\u3067\u6cbb\u7642\u3055\u308c\u305f\u60a3\u8005\uff08RCT + HT\uff09\u306e\u5e83\u7bc4\u306a\u5206\u6790\u3067\u306f\u3001EORTC\u816b\u760d\u5b66\u53c2\u7167\u96c6\u56e3\u3068\u6bd4\u8f03\u3057\u3066\u3001*12\u30f6\u6708\u9593\u306b\u308f\u305f\u3063\u3066\u7dad\u6301\u3055\u308c\u305f\u3001\u611f\u60c5\u7684\u6a5f\u80fd\u3001\u793e\u4f1a\u7684\u6a5f\u80fd\u3001\u304a\u3088\u3073\u4e0d\u7720\u75c7\uff08SL\uff09*\u3092\u8a55\u4fa1\u3059\u308bQoL\u30b5\u30d6\u30b9\u30b1\u30fc\u30eb\u3067\u306e\u30b9\u30b3\u30a2\u306e\u6709\u610f\u306a\u6539\u5584\u304c\u793a\u3055\u308c\u307e\u3057\u305f\u3002[10]<\/span><\/span><\/li>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7de9\u548c\u30b1\u30a2\u306e\u5229\u76ca\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u7de9\u548c\u30b1\u30a2\u306e\u72b6\u6cc1\u3067\u306f\u3001\u6a19\u6e96\u6cbb\u7642\u306bHT\u3092\u8ffd\u52a0\u3059\u308b\u3053\u3068\u3067\u3001\u6cbb\u7642\u5f8c*3\u30f6\u6708\u3067\u75bc\u75db\uff08PA\uff09\u306e\u81e8\u5e8a\u7684\u306b\u95a2\u9023\u306e\u3042\u308b\u6539\u5584\u3068\u7d4c\u6e08\u7684\u56f0\u96e3\uff08FI\uff09*\u306e\u6e1b\u5c11\u306b\u3064\u306a\u304c\u308a\u3001\u60a3\u8005\u306e\u3088\u308a\u826f\u3044\u5168\u4f53\u7684\u306a\u72b6\u614b\u306b\u8ca2\u732e\u3057\u307e\u3057\u305f\u3002[10]<\/span><\/span><\/li>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u9032\u884c\u75be\u60a3\u306b\u304a\u3051\u308bQoL\u306e\u6539\u5584\uff08\u7d50\u8178\u76f4\u8178\u304c\u3093\uff09\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u4e2d\u671f\u304a\u3088\u3073\u9032\u884c\u671f\u7d50\u8178\u76f4\u8178\u304c\u3093\u60a3\u8005\u306b\u304a\u3051\u308b\u5316\u5b66\u7642\u6cd5\u88dc\u52a9\u9ad8\u5468\u6ce2\u6e29\u71b1\u7642\u6cd5\u3092\u8a55\u4fa1\u3057\u305f\u7814\u7a76\u3067\u306f\u3001\u4f75\u7528\u7642\u6cd5\u3092\u53d7\u3051\u305f\u30b0\u30eb\u30fc\u30d7\u304c4\u30b5\u30a4\u30af\u30eb\u6cbb\u7642\u5f8c\u306b\u6709\u610f\u306b\u9ad8\u3044\uff08\u6539\u5584\u3055\u308c\u305f\uff09QoL\u30b9\u30b3\u30a2\u3092\u793a\u3057\u3001HT\u304c\u6cbb\u7642\u52b9\u679c\u306b\u52a0\u3048\u3066QoL\u3092\u52b9\u679c\u7684\u306b\u6539\u5584\u3057\u3001\u540c\u6642\u306b\u826f\u597d\u306a\u5b89\u5168\u6027\u3092\u7dad\u6301\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002[11]<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<hr \/>\n<section>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">4. \u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u514d\u75ab\u5b66\u7684\u5229\u76ca\u3068\u512a\u308c\u305f\u6cbb\u7642\u6307\u6570<\/span><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HT\u306f\u3001\u91cd\u5ea6\u306e\u6bd2\u6027\uff08\u30b0\u30ec\u30fc\u30c93-4\uff09\u306e\u30ea\u30b9\u30af\u3092\u5927\u5e45\u306b\u5897\u52a0\u3055\u305b\u308b\u3053\u3068\u306a\u304f\u6cbb\u7642\u306e\u81f4\u6b7b\u6027\u3092\u6700\u5927\u5316\u3057\u3001\u305d\u308c\u306b\u3088\u3063\u3066\u9ad8\u3044\u6cbb\u7642\u6307\u6570\u3092\u7dad\u6301\u3057\u307e\u3059\uff1a<\/span><\/span><\/p>\n<ul>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u691c\u8a3c\u3055\u308c\u305f\u5b89\u5168\u6027\uff08\u7b2cIII\u76f8\u81e8\u5e8a\u8a66\u9a13\uff09\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u5b50\u5bae\u9838\u304c\u3093\u306b\u304a\u3051\u308b\u30e1\u30bf\u30a2\u30ca\u30ea\u30b7\u30b9\u306f\u3001\u6025\u6027\u307e\u305f\u306f\u6669\u671f\u6bd2\u6027\u306b \u6709\u610f\u306a\u5dee\u304c\u306a\u3044 \u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\uff08RR\u6bd2\u6027 1.01\uff09[6]\u3002\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u76f4\u8178\u304c\u3093\u304a\u3088\u3073\u81b5\u81d3\u304c\u3093\u306e\u8a66\u9a13\u3067\u7dad\u6301\u3055\u308c\u3066\u3044\u307e\u3059\u3002[7][8]<\/span><\/span><\/li>\n<li><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u81d3\u5668\u6e29\u5b58\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u76f4\u8178\u304c\u3093\u3067\u306f\u3001\u30cd\u30aa\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u5316\u5b66\u653e\u5c04\u7dda\u7642\u6cd5\u3078\u306eHT\u306e\u8ffd\u52a0\u306b\u3088\u308a\u30015\u5e74\u9593\u306e\u4eba\u5de5\u809b\u9580\u975e\u4f9d\u5b58\u751f\u5b58\u7387\uff08CFS\uff09\u304c69.0%\u304b\u3089 87.7% \u306b\u5897\u52a0\u3057\u3001QoL\u306b\u3068\u3063\u3066\u4e3b\u8981\u306a\u6a5f\u80fd\u7684\u5229\u76ca\u3068\u306a\u308a\u307e\u3059\u3002[7]<\/span><\/span><\/li>\n<li><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><strong>\u30a2\u30d6\u30b9\u30b3\u30d1\u30eb\u52b9\u679c\uff08\u30ef\u30af\u30c1\u30f3\u69d8\uff09\uff1a<\/strong> HT\u306f *\u514d\u75ab\u539f\u6027\u7d30\u80de\u6b7b*\u3092\u8a98\u767a\u3057\u3001\u7d30\u80de\u50b7\u5bb3\u6027CD8+ T\u7d30\u80de\u3092\u6d3b\u6027\u5316\u3059\u308b *\u30d2\u30fc\u30c8\u30b7\u30e7\u30c3\u30af\u30d7\u30ed\u30c6\u30a4\u30f3\uff08HSP\uff09*\u3092\u653e\u51fa\u3057\u307e\u3059\u3002\u3053\u306e\u5168\u8eab\u7684\u306a\u514d\u75ab\u5b66\u7684\u30d7\u30e9\u30a4\u30df\u30f3\u30b0\u306f\u3001\u6b8b\u5b58\u75be\u60a3\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u306b\u8ca2\u732e\u3057\u3001\u672c\u8cea\u7684\u306a\u30a2\u30b8\u30e5\u30d0\u30f3\u30c8\u5229\u76ca\u3067\u3059\u3002[9]<\/span><\/span><\/li>\n<\/ul>\n<\/section>\n<hr \/>\n<section>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7d50\u8ad6\uff1a\u60a3\u8005\u4e2d\u5fc3\u306e\u6cbb\u7642<\/span><\/span><\/h2>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6e29\u71b1\u7642\u6cd5\u306e\u816b\u760d\u30d7\u30ed\u30c8\u30b3\u30eb\u3078\u306e\u7d71\u5408\u306f\u3001\u751f\u5b58\u7387\u3092\u6539\u5584\u3059\u308b\u3060\u3051\u3067\u306a\u304f\u3001\u5f37\u529b\u306a\u75c7\u72b6\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3092\u63d0\u4f9b\u3057\u3001\u751f\u6d3b\u306e\u8cea\u3092\u7dad\u6301\u3059\u308b\u3001\u9ad8\u5ea6\u306a\u3001\u8a3c\u62e0\u306b\u57fa\u3065\u3044\u305f\u6226\u7565\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002\u75bc\u75db\u7de9\u548c\u3001\u75b2\u52b4\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u3001\u304a\u3088\u3073\u512a\u308c\u305f\u5b89\u5168\u6027\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u306f\u3001HT\u3092\u816b\u760d\u60a3\u8005\u306e\u30db\u30ea\u30b9\u30c6\u30a3\u30c3\u30af\u30b1\u30a2\u306e\u4e0d\u53ef\u6b20\u306a\u8981\u7d20\u306b\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/p>\n<p style=\"text-align: center;\"><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6709\u52b9\u6027\u3068\u751f\u6d3b\u306e\u8cea\u306e\u4e21\u65b9\u3092\u6700\u5927\u5316\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u306b\u3001\u6e29\u71b1\u7642\u6cd5\u3092\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u7d71\u5408\u3059\u308b\u305f\u3081\u306b\u5c02\u9580\u5bb6\u306b\u3054\u76f8\u8ac7\u3044\u305f\u3060\u304f\u3053\u3068\u3092\u304a\u52e7\u3081\u3057\u307e\u3059\u3002<\/span><\/span><\/strong><\/p>\n<\/section>\n<footer>\n<hr \/>\n<p><small><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">EEAT\u4fdd\u8a3c\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> \u3053\u306e\u30b3\u30f3\u30c6\u30f3\u30c4\u306f\u3001\u751f\u6d3b\u306e\u8cea\u6e2c\u5b9a\u306e\u305f\u3081\u306e\u6a19\u6e96\u5316\u3055\u308c\u305f\u30c4\u30fc\u30eb\uff08EORTC QLQ-C30\uff09\u3092\u4f7f\u7528\u3057\u305f\u3001\u516c\u958b\u3055\u308c\u305f\u7b2cIII\u76f8\u7121\u4f5c\u70ba\u5316\u304a\u3088\u3073\u524d\u5411\u304d\u81e8\u5e8a\u8a66\u9a13\u306e\u30c7\u30fc\u30bf\u306b\u57fa\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u5b8c\u5168\u306a\u53c2\u7167\u6587\u732e\u306f\u3001\u51fa\u5178\u51fa\u7248\u7269\u3078\u306e\u76f4\u63a5\u30ea\u30f3\u30af\u3068\u3068\u3082\u306b\u7d71\u5408\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/small><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u53c2\u7167\u6587\u732e\uff1a<\/span><\/span><\/p>\n<ol>\n<li>Chi MS, Yang KL, Chang YC, Ko HL, Lin YH, Huang SC, Huang YY, Liao KW, Kondo M, Chi KH. Comparing the Effectiveness of Combined External Beam Radiation and Hyperthermia Versus External Beam Radiation Alone in Treating Patients With Painful Bony Metastases: A Phase 3 Prospective, Randomized, Controlled Trial. Int J Radiat Oncol Biol Phys. 2018 Jan 1;100(1):78-87. doi: 10.1016\/j.ijrobp.2017.09.030. Epub 2017 Sep 21. PMID: 29066122.<\/li>\n<li>Faghihi Moghaddam F, Bakhshandeh M, Mofid B, Sahinbas H, Faeghi F, Mirzaei H, Rakhsha A, Yousefi Kashi AS, Sadeghi R, Mahdavi A. Clinical effectiveness of combined whole body hyperthermia and external beam radiation therapy (EBRT) versus EBRT alone in patients with painful bony metastases: A phase III clinical trial study. J Therm Biol. 2024 Feb;120:103804. doi: 10.1016\/j.jtherbio.2024.103804. Epub 2024 Feb 23. PMID: 38460451.<\/li>\n<li>Minnaar CA, Maposa I, Kotzen JA, Baeyens A. Effects of Modulated Electro-Hyperthermia (mEHT) on Two and Three Year Survival of Locally Advanced Cervical Cancer Patients. Cancers (Basel). 2022 Jan 27;14(3):656. doi: 10.3390\/cancers14030656. PMID: 35158924; PMCID: PMC8833695.<\/li>\n<li>Ostberg, K., et al. The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis. Clin Rheumatol. 2008 Jul;27(7):849-56. doi: 10.1007\/s10067-007-0785-5. Epub 2007 Oct 20. PMID: 17948286.<\/li>\n<li>Morgan RB, Tun S, Eng OS. Quality of life after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: a narrative review. Curr Probl Surg. 2020 Jan;57(1):100693. doi: 10.1016\/j.cpsurg.2019.100693. Epub 2020 Jan 29. PMID: 32063294.<\/li>\n<li>Chia BSH, Ho SZ, Tan HQ, Chua MLK, Tuan JKL. A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers. Cancers (Basel). 2023 Jan 5;15(2):346. doi: 10.3390\/cancers15020346. PMID: 36672300; PMCID: PMC9856725.<\/li>\n<li>Ott, O.J., Schmidt, M., Semrau, S.\u00a0<i>et al.<\/i>\u00a0Chemoradiotherapy with and without deep regional hyperthermia for squamous cell carcinoma of the anus.\u00a0<i>Strahlenther Onkol<\/i>\u00a0<b>195<\/b>, 607\u2013614 (2019). <a href=\"https:\/\/doi.org\/10.1007\/s00066-018-1396-x\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.1007\/s00066-018-1396-x<\/a><\/li>\n<li>Fiorentini G, Sarti D, Mambrini A, Hammarberg Ferri I, Bonucci M, Sciacca PG, Ballerini M, Bonanno S, Milandri C, Nani R, Guadagni S, Dentico P, Fiorentini C. Hyperthermia combined with chemotherapy\u00a0<i>vs<\/i>\u00a0chemotherapy in patients with advanced pancreatic cancer: A multicenter retrospective observational comparative study. World J Clin Oncol. 2023 Jun 24;14(6):215-226. doi: 10.5306\/wjco.v14.i6.215. PMID: 37398545; PMCID: PMC10311475.<\/li>\n<li>Baronzio, G. F., et al. Putative Abscopal Effect in Three Patients Treated by Combined Radiotherapy and Modulated Electrohyperthermia. Front Oncol. 2020 Nov 24;10:591932. doi: 10.3389\/fonc.2020.591932. PMID: 33324545; PMCID: PMC7721869.<\/li>\n<li>Linnenbank, W. I., et al. Real-World Analysis of Quality of Life and Toxicity in Cancer Patients Treated with Hyperthermia Combined with Radiochemotherapy. Cancers (Basel). 2023 Feb 1;15(3):880. doi: 10.3390\/cancers15030880. PMID: 36765790; PMCID: PMC9954584.<\/li>\n<li>Liu, Z. Clinical effects of high frequency hyperthermia-assisted irinotecan chemotherapy on patients with middle and advanced colorectal cancer and its safety assessment. Oncol Lett. 2019 Jan;17(1):215-220. doi: 10.3892\/ol.2018.9574. Epub 2018 Oct 12. PMID: 30655758; PMCID: PMC6313175.<\/li>\n<\/ol>\n<\/footer>\n<\/article>\n","protected":false},"excerpt":{"rendered":"<p>\u6a29\u5a01\u3068\u5c02\u9580\u6027 (EEAT): \u8457\u8005: Dr. Veronica Iatan , MD, \u304a\u3088\u3073 Cristian Gologan M.Sc , \u30a2\u30f3\u30c9\u30ed\u30e1\u30c7\u30a3\u30c3\u30af\u30cf\u30a4\u30d1\u30fc\u30b5\u30fc\u30df\u30a2 \u6e29\u71b1\u7642\u6cd5\uff08HT\uff09\u304c\u751f\u6d3b\u306e\u8cea\uff08QoL\uff09\u306b\u4e0e&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[943,107,22],"tags":[944,945,946,949,950,1081,1083,1082,832],"class_list":["post-11444","post","type-post","status-publish","format-standard","hentry","category-studii-clinice-ja","category-107","category-22","tag-calitatea-vietii-ja","tag-durere-ja","tag-hipertermie-oncologica-ja","tag-qol-ja","tag-studii-faza-iii-ja","tag-1081","tag-1083","tag-iii","tag-832"],"gutentor_comment":0,"_links":{"self":[{"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/posts\/11444","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/comments?post=11444"}],"version-history":[{"count":0,"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/posts\/11444\/revisions"}],"wp:attachment":[{"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/media?parent=11444"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/categories?post=11444"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/ja\/wp-json\/wp\/v2\/tags?post=11444"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}