{"id":2744,"date":"2017-08-12T11:01:57","date_gmt":"2017-08-12T11:01:57","guid":{"rendered":"https:\/\/andromedichyperthermia.com\/2017\/08\/12\/%e6%a8%99%e6%ba%96%e7%9a%84%e3%81%8c%e3%82%93%e6%b2%bb%e7%99%82%e3%81%a8%e4%bd%b5%e7%94%a8%e3%81%97%e3%81%9f%e6%b7%b1%e9%83%a8%e5%b1%80%e6%89%80%e6%b8%a9%e7%86%b1%e7%99%82%e6%b3%95%e3%81%ae%e5%8f%af\/"},"modified":"2025-09-06T13:45:52","modified_gmt":"2025-09-06T13:45:52","slug":"%e6%b7%b1%e9%83%a8%e6%b8%a9%e7%86%b1%e7%99%82%e6%b3%95%ef%bc%88wbrt%ef%bc%89%e3%81%ab%e3%82%88%e3%82%8b%e8%84%b3%e8%bb%a2%e7%a7%bb%e3%81%ae%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a8%93","status":"publish","type":"post","link":"https:\/\/andromedichyperthermia.com\/ja\/%e6%b7%b1%e9%83%a8%e6%b8%a9%e7%86%b1%e7%99%82%e6%b3%95%ef%bc%88wbrt%ef%bc%89%e3%81%ab%e3%82%88%e3%82%8b%e8%84%b3%e8%bb%a2%e7%a7%bb%e3%81%ae%e8%87%a8%e5%ba%8a%e8%a9%a6%e9%a8%93\/","title":{"rendered":"\u6df1\u90e8\u5c40\u6240\u6e29\u71b1\u7642\u6cd5\u3068\u6a19\u6e96\u7684\u306a\u764c\u6cbb\u7642\u3092\u95a2\u9023\u4ed8\u3051\u3001\u53cd\u5fdc\u30d1\u30bf\u30fc\u30f3\u3092\u8a18\u8ff0\u3059\u308b\u6e96\u5b9f\u73fe\u53ef\u80fd\u6027\u81e8\u5e8a\u8a66\u9a13"},"content":{"rendered":"<h1 style=\"text-align: center;\">\u00a0<a href=\"https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2025\/02\/Deep-regional-hyperthermia-in-combination-with-whole-brain-radiotherapy-wbrt-in-poor-prognosis-patients-with-brain-metastases.pdf\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8133\u8ee2\u79fb\u3092\u6709\u3059\u308b\u4e88\u5f8c\u4e0d\u826f\u60a3\u8005\u306b\u304a\u3051\u308b\u5168\u8133\u653e\u5c04\u7dda\u7642\u6cd5\uff08WBRT\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u6df1\u90e8\u5c40\u6240\u6e29\u71b1\u7642\u6cd5<\/span><\/span><\/a><\/h1>\n<figure id=\"attachment_6979\" aria-describedby=\"caption-attachment-6979\" style=\"width: 567px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-6979 size-full\" src=\"https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2017\/08\/Deep-local-hyperthermia-in-combination-with-Whole-Brain-RadioTherapy-WBRT-in-Poor-Prognosis-Patients-with-Brain-Metastases.jpg\" alt=\"\u8133\u8ee2\u79fb\u3092\u6709\u3059\u308b\u4e88\u5f8c\u4e0d\u826f\u60a3\u8005\u306b\u304a\u3051\u308b\u5168\u8133\u653e\u5c04\u7dda\u7642\u6cd5\uff08WBRT\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u6df1\u90e8\u5c40\u6240\u6e29\u71b1\u7642\u6cd5\u306e\u81e8\u5e8a\u8a66\u9a13\" width=\"567\" height=\"776\" title=\"\" srcset=\"https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2017\/08\/Deep-local-hyperthermia-in-combination-with-Whole-Brain-RadioTherapy-WBRT-in-Poor-Prognosis-Patients-with-Brain-Metastases.jpg 567w, https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2017\/08\/Deep-local-hyperthermia-in-combination-with-Whole-Brain-RadioTherapy-WBRT-in-Poor-Prognosis-Patients-with-Brain-Metastases-219x300.jpg 219w\" sizes=\"auto, (max-width: 567px) 100vw, 567px\" \/><figcaption id=\"caption-attachment-6979\" class=\"wp-caption-text\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8133\u8ee2\u79fb\u3092\u6709\u3059\u308b\u4e88\u5f8c\u4e0d\u826f\u60a3\u8005\u306b\u304a\u3051\u308b\u5168\u8133\u653e\u5c04\u7dda\u7642\u6cd5\uff08WBRT\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u6df1\u90e8\u5c40\u6240\u6e29\u71b1\u7642\u6cd5<\/span><\/span><\/figcaption><\/figure>\n<h2><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u81e8\u5e8a\u8a66\u9a13<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6982\u8981<\/span><\/span><\/strong><\/h2>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u76ee\u7684:<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3053\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u76ee\u7684\u306f\u3001\u4e88\u5f8c\u4e0d\u826f\u8133\u8ee2\u79fb (GPI\u22642.5) \u60a3\u8005\u306b\u304a\u3051\u308b\u653e\u5c04\u7dda\u7642\u6cd5\u304a\u3088\u3073\u5168\u8eab\u7642\u6cd5\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u5c40\u6240\u6df1\u90e8\u6e29\u71b1\u7642\u6cd5\u306e\u5f79\u5272\u3092\u521d\u3081\u3066\u8a55\u4fa1\u3059\u308b\u3053\u3068\u3067\u3059\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u65b9\u6cd5\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u8133\u8ee2\u79fb\u304c\u78ba\u8a8d\u3055\u308c\u3001GPI\u30b9\u30b3\u30a2\u304c2.5\u4ee5\u4e0b\u3068\u5206\u985e\u3055\u308c\u305f\u60a3\u8005\u3092\u672c\u524d\u5411\u304d\u7814\u7a76\u306e\u5bfe\u8c61\u3068\u3057\u305f\u3002\u6cbb\u7642\u524d\u306e\u5c64\u5225\u5316\u306f\u3001GPI\u30b9\u30b3\u30a20\uff5e1\u306e\u60a3\u8005\uff08A\u7fa4\uff09\u3068GPI\u30b9\u30b3\u30a21.5\uff5e2.5\u306e\u60a3\u8005\uff08B\u7fa4\uff09\u3068\u5b9a\u7fa9\u3057\u305f\u3002\u5c40\u6240\u7642\u6cd5\u4e2d\u306b\u300113.56MHz\u306e\u9ad8\u5468\u6ce2\u3067\u3001\u5c40\u6240\u5bb9\u91cf\u6027\u6e29\u71b1\u7642\u6cd5\u88c5\u7f6e\uff08<\/span><\/span><a href=\"http:\/\/andromedic.it\" target=\"_blank\" rel=\"noopener\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u30a2\u30f3\u30c9\u30ed\u30e1\u30c7\u30a3\u30c3\u30af\u793e\u88fd<\/span><\/span><\/a> <a href=\"https:\/\/andromedichyperthermia.com\/andromedic-hydeep-600wm-deep-local-hyperthermia-device-2\/\"><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HyDeep 600WM<\/span><\/span><\/a><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff09\u3092\u7528\u3044\u3066\u3001\u90312\u56de\u30011\u56de60\u5206\u9593\u306e\u6e29\u71b1\u7642\u6cd5\u3092\u5b9f\u65bd\u3057\u305f\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7d50\u679c\uff1a<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\"> 2015\u5e746\u6708\u304b\u30892017\u5e746\u6708\u306e\u9593\u306b\u300115\u540d\u306e\u60a3\u8005\u3068\u5408\u8a0849\u306e\u8133\u8ee2\u79fb\u304c\u672c\u30d7\u30ed\u30c8\u30b3\u30eb\u306b\u542b\u307e\u308c\u307e\u3057\u305f\u3002\u5168\u60a3\u8005\u304c\u8a08\u753b\u901a\u308aHT\u30bb\u30c3\u30b7\u30e7\u30f3\u3092\u3059\u3079\u3066\u53d7\u3051\u307e\u3057\u305f\u3002\u653e\u5c04\u7dda\u7642\u6cd5\u3068\u5168\u8eab\u7642\u6cd5\u3082\u898f\u5b9a\u901a\u308a\u306b\u5b8c\u4e86\u3057\u307e\u3057\u305f\u3002<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6cbb\u7642\u306b\u5bfe\u3059\u308b\u5fcd\u5bb9\u6027\u306f\u826f\u597d\u3067\u3001\u6bd2\u6027\u306f\u8a8d\u3081\u3089\u308c\u307e\u305b\u3093\u3067\u3057\u305f\u3002HT\u6709\u52b9\u6cbb\u7642\u671f\u9593\u304c\u4e2d\u592e\u5024\u3088\u308a\u9577\u304b\u3063\u305f\u60a3\u8005\uff08W90time&gt;88%\uff09\u306f\u3001HT\u6709\u52b9\u6cbb\u7642\u671f\u9593\u304c\u4e2d\u592e\u5024\u3088\u308a\u77ed\u304b\u3063\u305f\u60a3\u8005\uff08\u305d\u308c\u305e\u308c50%\u30680%\uff09\u3068\u6bd4\u8f03\u3057\u3066\u30016\u30f6\u6708\u304a\u3088\u307312\u30f6\u6708\u6642\u70b9\u3067\u306e\u5b9f\u6e2cPFS\u304c\u826f\u597d\u3067\u3057\u305f\uff08\u305d\u308c\u305e\u308c100%\u306866.7%\uff09<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\uff08p&lt;0.031\uff09\u3002OS\u306e\u4e2d\u592e\u5024\u306f6\u30f6\u6708\uff08\u7bc4\u56f21\uff5e36\u30f6\u6708\uff09\u3067\u3057\u305f\u3002 GPI\u30b9\u30b3\u30a2\u306b\u3088\u308b\u5c64\u5225\u5316\u3067\u306f\u3001\u30b0\u30eb\u30fc\u30d7A\u306eOS\u4e2d\u592e\u5024\u306f3\u304b\u6708\uff08CI 95% 2.49-3.51\uff09\u3001\u30b0\u30eb\u30fc\u30d7B\u306eOS\u4e2d\u592e\u5024\u306f8.0\u304b\u6708\uff08CI 95% 5.1510.41\uff09\u3067\u3057\u305f\uff08p=0.035\uff09\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u7d50\u8ad6\uff1a<\/span><\/span><\/strong> <strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5c40\u6240\u6e29\u71b1\u7642\u6cd5\u306f\u3001\u8133\u8ee2\u79fb\u60a3\u8005\u306b\u304a\u3044\u3066\u653e\u5c04\u7dda\u6cbb\u7642\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u4f7f\u7528\u200b\u200b\u3067\u304d\u308b\u5b9f\u884c\u53ef\u80fd\u304b\u3064\u5b89\u5168\u306a\u6280\u8853\u3067\u3042\u308a\u3001\u4e88\u5f8c\u4e0d\u826f\u8133\u8ee2\u79fb\u60a3\u8005\u306ePFS\u304a\u3088\u3073\u751f\u5b58\u7387\u3092\u6539\u5584\u3059\u308b\u3002<\/span><\/span><\/strong><\/p>\n<p>&nbsp;<\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u672c\u7814\u7a76\u3067\u306f\u3001GPA\u30b9\u30b3\u30a2\u304c\u6700\u3082\u4e88\u5f8c\u4e0d\u826f\u306a\u7fa4\u306b\u5c5e\u3059\u308b15\u540d\u306e\u60a3\u800549\u4f8b\u306e\u8133\u8ee2\u79fb\u3092\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002\u30b9\u30b3\u30a2\u6307\u6570\u304c0\uff5e1\u306e\u60a3\u80056\u540d\uff08A\u7fa4\uff09\u3001\u30b9\u30b3\u30a2\u6307\u6570\u304c1.5\uff5e2.5\u306e\u60a3\u80059\u540d\uff08B\u7fa4\uff09\u3092\u5bfe\u8c61\u3068\u3057\u307e\u3057\u305f\u3002\u5168\u60a3\u8005\u306f\u653e\u5c04\u7dda\u7642\u6cd5\u3068\u5c40\u6240\u7642\u6cd5\u306e\u4f75\u7528\u7642\u6cd5\u3092\u53d7\u3051\u307e\u3057\u305f\u3002\u672c\u7814\u7a76\u306e\u7b2c\u4e00\u306e\u7d50\u8ad6\u306f\u3001\u653e\u5c04\u7dda\u7642\u6cd5\u3068\u5c40\u6240\u7642\u6cd5\u306e\u4f75\u7528\u7642\u6cd5\u306f\u8133\u8ee2\u79fb\u60a3\u8005\u306b\u3068\u3063\u3066\u5fcd\u5bb9\u6027\u306e\u9ad8\u3044\u6cbb\u7642\u3067\u3042\u308b\u3068\u3044\u3046\u3053\u3068\u3067\u3059\u3002\u3059\u3079\u3066\u306e\u6cbb\u7642\u306f\u51e6\u65b9\u901a\u308a\u306b\u5b9f\u65bd\u3055\u308c\u307e\u3057\u305f<\/span><\/span><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002<\/span><\/span><\/strong><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HT\u306b\u3088\u308b\u6bd2\u6027\u306f\u8a8d\u3081\u3089\u308c\u306a\u304b\u3063\u305f\u3002\u4e00\u65b9\u3001Byun\u3089[13]\u306f\u8853\u4e2dHT\u306b\u95a2\u3059\u308b\u7814\u7a76\u306b\u304a\u3044\u3066\u3001\u4f75\u7528\u7642\u6cd5\u306e\u5408\u4f75\u75c7\u3068\u3057\u3066\u3001\u76f8\u5f53\u6570\u306e\u75c7\u4f8b\u3067\u767a\u4f5c\u3068\u5275\u50b7\u611f\u67d3\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/span><\/span><\/strong> <strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u6df1\u90e8\u6e29\u71b1\u7642\u6cd5\u306f\u3001\u8907\u96d1\u306a\u8853\u4e2d\u7642\u6cd5\u3088\u308a\u3082\u5bb9\u6613\u304b\u3064\u5b89\u5168\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u308b<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">HT\u6cbb\u7642\u306e\u8cea\uff08W90\u6642\u9593 &gt; 88%\uff09\u306f\u3001\u751f\u5b58\u306e\u6700\u3082\u5f37\u529b\u306a\u4e88\u6e2c\u56e0\u5b50\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u3064\u307e\u308a\u3001\u51e6\u65b9\u3055\u308c\u305f\u51fa\u529b\u306e90%\uff08150W\uff09\u3067\u6cbb\u7642\u6642\u9593\u306e88%\u4ee5\u4e0a\u3092\u7167\u5c04\u3055\u308c\u305f\u60a3\u8005\u306f\u3001\u512a\u308c\u305fPFS\u7387\u3092\u793a\u3057\u3066\u304a\u308a\u3001HT\u304c\u816b\u760d\u306e\u653e\u5c04\u7dda\u5316\u5b66\u7642\u6cd5\u306b\u5bfe\u3059\u308b\u611f\u53d7\u6027\u3092\u9ad8\u3081\u308b\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059[4-7]\u3002<\/span><\/span><\/p>\n<p><strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u5168\u751f\u5b58\u7387\u306b\u3088\u308b\u3068\u3001\u672c\u7814\u7a76\u306b\u304a\u3051\u308b\u5168\u751f\u5b58\u671f\u9593\u306e\u4e2d\u592e\u5024\u306f6\u30f6\u6708\u3067\u3042\u308a\u3001\u3053\u308c\u3089\u306e\u75c7\u4f8b\u306b\u304a\u3051\u308b\u6a19\u6e96\u6cbb\u7642\u306e\u4e0d\u826f\u306a\u6210\u7e3e\u3092\u6539\u5584\u3057\u307e\u3057\u305f[3]\u3002\u6e29\u71b1\u7642\u6cd5\u3068\u653e\u5c04\u7dda\u7642\u6cd5+\/-\u5168\u8eab\u7642\u6cd5\u306e\u4f75\u7528\u306b\u3088\u308a\u3001\u8133\u8ee2\u79fb\u3092\u6709\u3059\u308b\u9aa8\u9ac4\u816b\u60a3\u8005\u306b\u304a\u3044\u3066\u30016\u30f6\u6708\u6642\u70b9\u3067\u306e\u751f\u5b58\u7387\u306f53.1%\u300112\u30f6\u6708\u6642\u70b9\u3067\u306e\u751f\u5b58\u7387\u306f30.6%\u306b\u9054\u3057\u307e\u3057\u305f<\/span><\/span><\/strong><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">\u3002<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">https:\/\/pubmed.ncbi.nlm.nih.gov\/32748093\/<\/span><\/span><\/p>\n<p><span dir=\"auto\" style=\"vertical-align: inherit;\"><span dir=\"auto\" style=\"vertical-align: inherit;\">https:\/\/link.springer.com\/article\/10.1007\/s12094-020-02404-9<\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00a0\u8133\u8ee2\u79fb\u3092\u6709\u3059\u308b\u4e88\u5f8c\u4e0d\u826f\u60a3\u8005\u306b\u304a\u3051\u308b\u5168\u8133\u653e\u5c04\u7dda\u7642\u6cd5\uff08WBRT\uff09\u3068\u7d44\u307f\u5408\u308f\u305b\u305f\u6df1\u90e8\u5c40\u6240\u6e29\u71b1\u7642\u6cd5 \u81e8\u5e8a\u8a66\u9a13\u6982\u8981 \u76ee\u7684:\u3053\u306e\u81e8\u5e8a\u8a66\u9a13\u306e\u76ee\u7684\u306f\u3001\u4e88\u5f8c\u4e0d\u826f\u8133\u8ee2\u79fb (GPI\u22642.5) 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