{"id":3839,"date":"2017-08-12T18:58:11","date_gmt":"2017-08-12T18:58:11","guid":{"rendered":"https:\/\/andromedichyperthermia.com\/deep-local-hyperthermia-meht\/"},"modified":"2026-02-11T11:52:23","modified_gmt":"2026-02-11T11:52:23","slug":"moduleta-rf-hipertermija","status":"publish","type":"page","link":"https:\/\/andromedichyperthermia.com\/lv\/moduleta-rf-hipertermija\/","title":{"rendered":"Modul\u0113ta RF-Hipertermija  ( 13,56 MHz RF mHT + RF specifiska patolo\u0123ijai )"},"content":{"rendered":"<p><script type=\"application\/ld+json\">\n{\n  \"@context\": \"https:\/\/schema.org\",\n  \"@graph\": [\n    {\n      \"@type\": \"Article\",\n      \"@id\": \"https:\/\/andromedichyperthermia.com\/lv\/moduleta-rf-hipertermija\/#article\",\n      \"mainEntityOfPage\": {\n        \"@type\": \"WebPage\",\n        \"@id\": \"https:\/\/andromedichyperthermia.com\/lv\/moduleta-rf-hipertermija\/\"\n      },\n      \"headline\": \"Modul\u0113t\u0101 RF hipertermija - 13,56 MHz mHT\",\n      \"description\": \"Modul\u0113t\u0101 RF hipertermija (mHT) ir progres\u012bva sild\u012b\u0161anas terapija, kas selekt\u012bvi m\u0113r\u0137\u0113 un izn\u012bcina \u013caundab\u012bg\u0101s \u0161\u016bnas, nekait\u0113jot veselajiem audiem. \u0160\u012b jaun\u0101k\u0101s paaudzes medic\u012bnisk\u0101 inov\u0101cija nodro\u0161ina prec\u012bzu, kontrol\u0113tu un dzi\u013cu ener\u0123iju (kombin\u0113jot hipertermisko un elektromagn\u0113tisko iedarb\u012bbu), izmantojot kapacit\u012bvi saist\u012btu 13,56 MHz amplit\u016bdas modul\u0113tu radiofrekvenci, uzlabojot \u0137\u012bmijterapijas, staru terapijas un im\u016bnterapijas efektivit\u0101ti.\",\n      \"image\": {\n        \"@type\": \"ImageObject\",\n        \"url\": \"https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2025\/07\/modulated-RF-HT-selective-cancer-cells-300x213.jpg\",\n        \"width\": 300,\n        \"height\": 213,\n        \"caption\": \"Modul\u0113t\u0101 RF HT selekt\u012bva v\u0113\u017ea 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dzi\u013cas lok\u0101l\u0101s hipertermijas sist\u0113ma\/ier\u012bce, modul\u0113t\u0101s RF hipertermijas sist\u0113ma\/ier\u012bce un elektro-hipertermijas sist\u0113ma\/ier\u012bce.\",\n          \"manufacturer\": { \"@id\": \"https:\/\/andromedichyperthermia.com\/#organization\" },\n          \"url\": \"https:\/\/andromedichyperthermia.com\/lv\/onkologiskas-hipertermijas-ierice\/\"\n        },\n        {\n          \"@type\": \"MedicalTherapy\",\n          \"name\": \"Chemotherapy\",\n          \"url\": \"https:\/\/www.kosinmedj.org\/journal\/view.php?number=1294\"\n        },\n        {\n          \"@type\": \"MedicalTherapy\",\n          \"name\": \"Radiotherapy\",\n          \"url\": \"https:\/\/www.kosinmedj.org\/journal\/view.php?number=1294\"\n        },\n        {\n          \"@type\": \"MedicalTherapy\",\n          \"name\": \"Immunotherapy\",\n          \"url\": \"https:\/\/www.mdpi.com\/2072-6694\/15\/18\/4569\"\n        }\n      ],\n      \"mentions\": [\n        { \"@type\": \"Thing\", \"name\": \"13.56 MHz\", \"description\": \"Radiofrequency carrier frequency\" },\n        { \"@type\": \"Thing\", \"name\": \"RF modulation\" },\n        { \"@type\": \"Thing\", \"name\": \"Electromagnetic effects\" },\n        { \"@type\": \"Thing\", \"name\": \"Thermal effects\" },\n        { \"@type\": \"Thing\", \"name\": \"Capacitively coupled\" },\n        { \"@type\": \"Thing\", \"name\": \"Impedance\" },\n        { \"@type\": \"Thing\", \"name\": \"Extracellular electrolyte\" },\n        { \"@type\": \"Thing\", \"name\": \"DNA repair mechanism\" },\n        { \"@type\": \"Thing\", \"name\": \"Perfusion\" },\n        { \"@type\": \"Thing\", \"name\": \"Oxygenation\" },\n        { \"@type\": \"Thing\", \"name\": \"Vasodilation effect\" },\n        { \"@type\": \"Thing\", \"name\": \"Radio sensitization\" },\n        { \"@type\": \"Thing\", \"name\": \"Tumor Micro Environment\", \"alternateName\": \"TME\" },\n        { \"@type\": \"Thing\", \"name\": \"DAMP\", \"description\": \"Danger-Associated Molecular Patterns\" },\n        { \"@type\": \"Thing\", \"name\": \"Immunogenic Cell Death\", \"alternateName\": \"ICD\" },\n        { \"@type\": \"Thing\", \"name\": \"Heat Shock Proteins\", \"alternateName\": \"HSPs\" },\n        { \"@type\": \"Thing\", \"name\": \"Natural Killer cells\", \"alternateName\": \"NK cells\" },\n        { \"@type\": \"Thing\", \"name\": \"Dendritic cells\", \"alternateName\": \"DC cells\" },\n        { \"@type\": \"Thing\", \"name\": \"Cytotoxic T lymphocytes\", \"alternateName\": \"CTL\" },\n        { \"@type\": \"Thing\", \"name\": \"Helper T cells\", \"alternateName\": \"Th1\" },\n        { \"@type\": \"Thing\", \"name\": \"Memory T cells\", \"alternateName\": \"Tmemory\" },\n        { \"@type\": \"Thing\", \"name\": \"Abscopal effect\" },\n        { \"@type\": \"Thing\", \"name\": \"Overall Survival\", \"alternateName\": \"OS\" },\n        { \"@type\": \"Thing\", \"name\": \"Quality of Life\", \"alternateName\": \"QoL\" },\n        { \"@type\": \"Thing\", \"name\": \"Adjuvant therapy\" },\n        { \"@type\": \"Thing\", \"name\": \"Neoadjuvant therapy\" },\n        { \"@type\": \"Thing\", \"name\": \"Palliative therapy\" },\n        { \"@type\": \"Person\", \"name\": \"Hegyi G\" },\n        { \"@type\": \"Person\", \"name\": \"Szasz O\" },\n        { \"@type\": \"Person\", \"name\": \"Szasz A\" },\n        { \"@type\": \"Person\", \"name\": \"Ralph Kleef\" },\n        { \"@type\": \"Thing\", \"name\": \"Nivolumab\" },\n        { \"@type\": \"Thing\", \"name\": \"Ipilimumab\" },\n        { \"@type\": \"Thing\", \"name\": \"Interleukin 2\" }\n      ],\n      \"citation\": [\n        \"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5356646\/\",\n        \"https:\/\/www.kosinmedj.org\/journal\/view.php?number=1294#f1-kmj-24-127\",\n        \"https:\/\/www.mdpi.com\/2072-6694\/15\/18\/4569\",\n        \"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC9939221\/\",\n        \"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10663566\/\"\n      ]\n    },\n    {\n      \"@type\": \"MedicalOrganization\",\n      \"@id\": \"https:\/\/andromedichyperthermia.com\/#organization\",\n      \"name\": \"Andromedic Hyperthermia\",\n      \"url\": \"https:\/\/andromedichyperthermia.com\/lv\/\",\n      \"logo\": {\n        \"@type\": \"ImageObject\",\n        \"url\": \"https:\/\/andromedichyperthermia.com\/logo.png\"\n      }\n    }\n  ]\n}\n<\/script><\/p>\n<div class=\"mht-clinical-container\" style=\"max-width: 1100px; margin: 0 auto; font-family: 'Segoe UI', Roboto, Helvetica, Arial, sans-serif; color: #2c3e50; line-height: 1.7;\">\n<header style=\"border-bottom: 3px solid #004a99; margin-bottom: 30px; padding-bottom: 20px;\">\n<h1 style=\"color: #004a99; font-size: 2.4em; margin-bottom: 10px;\">Module\u0304ta RF hipertermija &#8211; 13,56 MHz mHT tehnolo\u0123ija<\/h1>\n<p style=\"font-size: 1.15em; font-weight: 400;\">Module\u0304ta\u0304 RF hipertermija (mHT) ir progres\u012bva sild\u012b\u0161anas terapija, kas izmanto <strong>siner\u0123isku termisko un netermisko (elektromagn\u0113tisko) iedarb\u012bbu<\/strong>, lai <strong>SELEKT\u012aVI<\/strong> kars\u0113tu un izn\u012bcin\u0101tu \u013caundab\u012bg\u0101s \u0161\u016bnas, neboj\u0101jot veselos audus.<\/p>\n<\/header>\n<div style=\"display: flex; flex-wrap: wrap; gap: 40px; margin-bottom: 50px; align-items: flex-start;\">\n<div style=\"flex: 1; min-width: 320px;\">\n<p>mHT ir jaun\u0101k\u0101s paaudzes medic\u012bnas inov\u0101cija, kas v\u0113\u017ea \u0161\u016bn\u0101m pievada <strong>selekt\u012bvu, kontrol\u0113tu un dzi\u013cu ener\u0123iju (hipertermisko + elektromagn\u0113tisko)<\/strong>, izmantojot kapacit\u012bvi saist\u012btu 13,56 MHz amplit\u016bdas modul\u0113tu radiofrekvenci.<\/p>\n<div style=\"background: #f0f7ff; border-left: 5px solid #004a99; padding: 20px; margin: 20px 0;\">\n<h2 style=\"margin-top: 0; color: #004a99; font-size: 1.3em;\">Augst\u0101k\u0101 l\u012bme\u0146a dzi\u013c\u0101 iedarb\u012bba onkolo\u0123ij\u0101<\/h2>\n<p>13,56 MHz mHT ar 2 elektrodiem sp\u0113j iek\u013c\u016bt l\u012bdz pat <strong>38,4 cm dzi\u013cum\u0101<\/strong> un ir pier\u0101d\u012bjusi p\u0101r\u0101kumu p\u0101r 8 MHz cCHT sist\u0113m\u0101m<br \/>\n<a style=\"color: #004a99; text-decoration: underline;\" title=\"Sal\u012bdzino\u0161ais p\u0113t\u012bjums par 13,56 MHz vs 8 MHz hipertermiju\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC5356646\/\" target=\"_blank\" rel=\"noopener\">(Atsauce)<\/a>.<\/p>\n<\/div>\n<p>mHT pievada termisko ener\u0123iju tikai audz\u0113ja \u0161\u016bnu membr\u0101nai un ekstracelul\u0101rajai matricai, izmantojot temperat\u016bru zem 43 \u00b0C, t\u0101d\u0113j\u0101di risinot tradicion\u0101l\u0101s hipertermijas ierobe\u017eojumus <strong>gandr\u012bz \u0161\u016bnu l\u012bmen\u012b<\/strong>.<\/p>\n<\/div>\n<div style=\"flex: 1; min-width: 320px; text-align: center;\">\n<figure style=\"margin: 0; background: #fff; padding: 15px; border: 1px solid #e1e8ed; border-radius: 8px; box-shadow: 0 4px 12px rgba(0,0,0,0.08);\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone\" style=\"width: 100%; height: auto; border-radius: 4px;\" title=\"mHT selekt\u012bvais meh\u0101nisms\" src=\"https:\/\/andromedichyperthermia.com\/wp-content\/uploads\/2025\/07\/modulated-RF-HT-selective-cancer-cells-300x213.jpg\" alt=\"module\u0304ta\u0304 RF-hipertermija mHT selekt\u012bv\u0101s m\u0113r\u0137\u0113\u0161anas meh\u0101nisms v\u0113\u017ea \u0161\u016bn\u0101s - HyDeep 600WM -\" width=\"300\" height=\"213\" \/><figcaption style=\"font-size: 0.9em; text-align: left; padding-top: 15px; line-height: 1.4; color: #576574;\"><strong>1. att\u0113ls. mHT selekt\u012bvais meh\u0101nisms.<\/strong> Modul\u0113t\u0101 radiofrekvences str\u0101va pl\u016bst galvenok\u0101rt ekstracelul\u0101raj\u0101 elektrol\u012bt\u0101, jo norm\u0101las \u0161\u016bnas elektroniski izol\u0113 vair\u0101k nek\u0101 viena miljona V\/m elektrisk\u0101 lauka stiprums <em>(Hegyi G, Szasz O, Szasz A. PMID: 24494322.)<\/em><\/figcaption><\/figure>\n<\/div>\n<\/div>\n<h2 style=\"color: #004a99; text-align: center; margin-bottom: 35px;\">Amplit\u016bdas modul\u0113t\u0101s RF hipertermijas kl\u012bniskie ieguvumi<\/h2>\n<div style=\"display: grid; grid-template-columns: repeat(auto-fit, minmax(320px, 1fr)); gap: 25px; margin-bottom: 50px;\">\n<div style=\"background: #fff; border: 1px solid #e1e8ed; border-top: 4px solid #004a99; padding: 25px; border-radius: 0 0 8px 8px;\">\n<h3 style=\"margin-top: 0; color: #004a99; font-size: 1.2em;\">\u0136\u012bmijterapijas un biolo\u0123iskais atbalsts<\/h3>\n<p style=\"font-size: 0.95em;\"><strong>Lab\u0101ka perf\u016bzija:<\/strong> Vazodilat\u0101cijas efekta d\u0113\u013c mHT nodro\u0161ina lab\u0101ku \u0137\u012bmijterapijas vai biolo\u0123isko vielu pieg\u0101di audz\u0113jam <a title=\"Kosin Medical Journal: Hipertermijas rezult\u0101ti\" href=\"https:\/\/www.kosinmedj.org\/journal\/view.php?number=1294\" target=\"_blank\" rel=\"noopener\">(atsauce)<\/a>, uzlabojot \u0101rst\u0113\u0161anas izn\u0101kumu.<\/p>\n<\/div>\n<div style=\"background: #fff; border: 1px solid #e1e8ed; border-top: 4px solid #004a99; padding: 25px; border-radius: 0 0 8px 8px;\">\n<h3 style=\"margin-top: 0; color: #004a99; font-size: 1.2em;\">Radiosensibiliz\u0101cija<\/h3>\n<p style=\"font-size: 0.95em;\">Izmai\u0146as audz\u0113ja un blakus eso\u0161o audu <strong>oksigen\u0101cij\u0101<\/strong> padara mHT par lielisku izv\u0113li pirms un p\u0113c staru terapijas, sensibiliz\u0113jot audz\u0113ju paaugstin\u0101tai starojuma efektivit\u0101tei <a title=\"P\u0113t\u012bjums par radiosensibiliz\u0101ciju un mHT\" href=\"https:\/\/www.kosinmedj.org\/journal\/view.php?number=1294\" target=\"_blank\" rel=\"noopener\">(atsauce)<\/a>.<\/p>\n<\/div>\n<div style=\"background: #fdf2f2; border: 1px solid #f8d7da; border-top: 4px solid #d9534f; padding: 25px; border-radius: 0 0 8px 8px;\">\n<h3 style=\"margin-top: 0; color: #c0392b; font-size: 1.2em;\">Imunog\u0113nie efekti (Abscopal)<\/h3>\n<p style=\"font-size: 0.9em; line-height: 1.5;\"><strong>ICD induc\u0113t\u0101js:<\/strong> mHT modul\u0113 audz\u0113ja mikrovidi (TME), ierosinot <strong>DAMP<\/strong> un <strong>HSP70<\/strong>. Tas aktiviz\u0113 NK \u0161\u016bnas un nobriedina dendr\u012btisk\u0101s \u0161\u016bnas (DC), radot sist\u0113misku reakciju uz att\u0101l\u0101m metast\u0101z\u0113m.<\/p>\n<div style=\"font-family: monospace; font-size: 0.85em; background: #fff; padding: 10px; border-radius: 4px; border: 1px dashed #d9534f; margin-top: 10px;\">mHT (ICD induc\u0113t\u0101js) -&gt; DAMP -&gt; HSP70 -&gt; DC -&gt; T-\u0161\u016bnas (CTL, Th1, Tmemory) -&gt; <strong>Sist\u0113miska pretv\u0113\u017ea reakcija<\/strong><\/div>\n<p style=\"font-size: 0.85em; margin-top: 10px; color: #7f8c8d;\">Pier\u0101d\u012bts p\u0101r\u0101kums p\u0101r nivolumabu un ipilimumabu GI v\u0113\u017ea gad\u012bjumos (Ralph Kleef et. al)<br \/>\n<a title=\"Ralph Kleef p\u0113t\u012bjums par mHT un im\u016bnterapiju\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC10663566\/\" target=\"_blank\" rel=\"noopener\">(atsauce)<\/a>.<\/p>\n<\/div>\n<\/div>\n<div style=\"background: #f8fbff; padding: 30px; border-radius: 12px; border: 1px solid #e1e8ed; margin-bottom: 50px;\">\n<h3 style=\"color: #004a99; margin-top: 0;\">Kl\u012bniskie rezult\u0101ti: dz\u012bvildze (OS) un dz\u012bves kvalit\u0101te (QoL)<\/h3>\n<p>Onkolo\u0123ij\u0101 kl\u012bniski vair\u0101kk\u0101rt ir pier\u0101d\u012bta <strong>kop\u0113j\u0101s dz\u012bvildzes (OS) pagarin\u0101\u0161an\u0101s<\/strong>, pievienojot mHT terapiju, papildus lok\u0101lai audz\u0113ja kontrolei un uzlabotai <strong>dz\u012bves kvalit\u0101tei (QoL)<\/strong> <a title=\"Kl\u012bniskie pier\u0101d\u012bjumi par OS un QoL ar mHT\" href=\"https:\/\/www.mdpi.com\/2072-6694\/15\/18\/4569\" target=\"_blank\" rel=\"noopener\">(atsauce)<\/a>.<\/p>\n<p style=\"font-style: italic; font-size: 0.95em; color: #576574;\">Atbalsta adjuvant\u0101, neoadjuvant\u0101 un paliat\u012bv\u0101 terapija neoplastisku patolo\u0123iju, infekciju, iekaisumu un s\u0101pju gad\u012bjumos.<\/p>\n<\/div>\n<section style=\"background: linear-gradient(135deg, #004a99 0%, #002d5d 100%); color: #fff; padding: 40px; border-radius: 15px; text-align: center; box-shadow: 0 10px 20px rgba(0,74,153,0.2);\">\n<h2 style=\"color: #fff; margin-top: 0; font-size: 1.8em;\">Uzlabota mHT: Andromedic HyDeep 600WM<\/h2>\n<p style=\"font-size: 1.1em; max-width: 800px; margin: 0 auto 25px auto;\">Andromedic module\u0304ta\u0304s hipertermijas ieri\u0304ce izmanto 13,56 MHz k\u0101 nes\u0113jfrekvenci un apvieno to ar <strong>radiofrekvenc\u0113m, kas ir specifiskas katrai patolo\u0123ijai un v\u0113\u017ea veidam<\/strong>, b\u016btiski uzlabojot klasisk\u0101s mHT rezult\u0101tus.<\/p>\n<p><a style=\"display: inline-block; background: #ffd700; color: #002d5d; padding: 15px 35px; border-radius: 30px; text-decoration: none; font-weight: bold; font-size: 1.1em; transition: transform 0.2s;\" href=\"https:\/\/andromedichyperthermia.com\/lv\/onkologiskas-hipertermijas-ierice\/\"><br \/>\nIepaz\u012bstiet HyDeep 600WM ier\u012bces tehnolo\u0123iju<br \/>\n<\/a><\/p>\n<\/section>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Modul\u0113t\u0101 RF hipertermija (mHT) ir sild\u012b\u0161anas terapija, kas izmanto siner\u0123isku termisko un netermisko (elektromagn\u0113tisko) iedarb\u012bbu, lai SELEKT\u012aVI kars\u0113tu un izn\u012bcin\u0101tu \u013caundab\u012bg\u0101s \u0161\u016bnas, neboj\u0101jot veselos audus. mHT ir jaun\u0101k\u0101s paaudzes medic\u012bnas inov\u0101cija, kas v\u0113\u017ea \u0161\u016bn\u0101m pievada selekt\u012bvu, kontrol\u0113tu un dzi\u013cu ener\u0123iju (hipertermisko + elektromagn\u0113tisko), izmantojot kapacit\u012bvi saist\u012btu 13,56 MHz amplit\u016bdas modul\u0113tu radiofrekvenci.<\/p>\n<p>13,56 MHz mHT ar diviem elektrodiem sp\u0113j iek\u013c\u016bt l\u012bdz pat 38,4 cm dzi\u013cum\u0101 un ir pier\u0101d\u012bjusi p\u0101r\u0101kumu p\u0101r 8 MHz cCHT sist\u0113m\u0101m. Turkl\u0101t Andromedic HyDeep 600WM (uzlabota onkolo\u0123isk\u0101s hipertermijas ier\u012bce) izmanto 13,56 MHz k\u0101 nes\u0113jfrekvenci un apvieno to ar radiofrekvenc\u0113m, kas ir specifiskas katrai patolo\u0123ijai un v\u0113\u017ea veidam, t\u0101d\u0113j\u0101di potenci\u0101li uzlabojot klasisk\u0101s 13,56 MHz mHT rezult\u0101tus.<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3839","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/pages\/3839","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/comments?post=3839"}],"version-history":[{"count":0,"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/pages\/3839\/revisions"}],"wp:attachment":[{"href":"https:\/\/andromedichyperthermia.com\/lv\/wp-json\/wp\/v2\/media?parent=3839"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}