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Andromedic HYDEEP 600WM Advanced Oncologic Hyperthermia Device: Local, Deep & Shallow Hyperthermia for Targeted Cancer Therapy – AndromedicHyperthermia / Call us Now
Andromedic HyDeep 600 WM
Advanced Modulated RF-Hyperthermia Device
The next generation of advanced oncological hyperthermia devices for cancer therapy. Delivering precisely controlled heat and electromagnetic energy selectively to cancer tissues, reaching depths of up to 38.4 cm.
advanced modulated 13.56 MHz & Pathology Specific RFs
CE / ISO 13485 / MDR / KGMP / MFDF Certified
Non-Invasive
CE / ISO 13485 / MDR / KGMP / MFDF Certified
Non-Invasive
Targeted Hyperthermia Therapy with the Andromedic HyDeep 600WM modulated RF Hyperthermia Device
The Andromedic HyDeep 600WM is a cutting-edge local hyperthermia device ( for deep & shallow cancers) designed for targeted RF-hyperthermia therapy.
It delivers precisely controlled heat + electromagnetic energy selectively to cancer tissues, offering a non-invasive treatment option for:
Superficial Tumors
Melanoma, epithelioma, cutaneous metastases, lymph node packs, superficial relapses.
Deep Seated Tumors
Sarcomas, lung cancer, pleura, pelvic cancer, bone cancer, gastrointestinal cancers (liver, pancreatic, colorectal, stomach), male & female genital cancers (ovarian, kidney & bladder & prostate cancer), brain tumors & head-neck tumors, tongue-pharyngeal cancer, laryngeal cancer, maxillofacial, jaw & cheeks cancers, etc.
Non-Oncological Pathologies:
This modulated RF hyperthermia device can also be used for inflammation, pain (including Lyme disease), endometriosis, adenomas, fibrosis, etc.
Customized Precision:
This deep local hyperthermia device has specific programmed protocols (time intervals, power in Watts, Radio Frequencies) for each pathology, adjusted according to patient’s height, weight & distance between the electrodes.
Key Features and Benefits
Advanced Modulated RF Hyperthermia (mHT)
Modulated RF-hyperthermia (mHT) is a heating therapy that uses synergized thermal and nonthermal (electromagnetic) effects to heat and destroy malignant cells in a SELECTIVE manner, without damaging healthy cells.
mHT is the latest generation medical innovation that delivers selective, controlled, and deep energy (hyperthermic + electromagnetic) using capacitively coupled 13.56 MHz amplitude modulated radiofrequency to cancer cells. The 13.56 MHz mHT with 2 electrodes can penetrate up to 38.4 cm in depth and has been shown superior to 8 MHz cCHT (ref).
Fig. 1. Selective mechanism of modulated RF-hyperthermia (mHT)
“Modulated radiofrequency (RF) current flows only through malignant conditions. The 13.56 MHz radiofrequency modulated current (fractally modulated) between 2 electrodes automatically focuses through malignant tissues with lower impedance and will flow mainly into the extracellular electrolyte because normal cells are electronically isolated from their membrane by more than one million V/m electric field strength.”
(Hegyi G, Szasz O, Szasz A. PMID: 24494322)
mHT has emerged as an innovative method to overcome the limitations of conventional hyperthermia. It is a far more targeted therapy, delivering thermal energy selectively only to the tumor cell membrane and extracellular matrix at temperatures below 43 °C. This solves the problem of deep selective action at the near cellular level, supported by in vivo, in vitro and human research.
The Benefits of 13.56 MHz Modulated RF Hyperthermia:
- ✔
Better perfusion: Of chemotherapeutic or biological substances (ref) and better treatment outcomes due to the vasodilation effect. - ✔
Radio sensitization: Due to changes in oxygenation of tumor and adjacent tissue (ref). - ✔
Clinical Outcome: Improved Overall Survival (OS), local tumor control, and increased Quality of Life (QoL) (ref).
Immunogenic Cell Death (ICD):
mHT acts as a monotherapy with local and abscopal effects and is synergistic with other immunotherapies (ref).
Mechanism: mHT (ICD inducer) → DAMPs → HSP70s → DCs → activation of tumor-specific T cells (CTLs, Th1, Tmemory) → systemic cytotoxic antitumor response.
Superior to nivolumab, ipilimumab, and interleukin 2 in gastrointestinal cancers (ref).
Andromedic HyDeep 600WM HT device Innovation: We use 13.56 MHz as a carrier RF and combine it with Radio Frequencies specific for each pathology and cancer type, aiming to improve the outcomes of classical 13.56 MHz mHT.
Advanced Modulation Protocol
Andromedic HY-DEEP 600WM mHT device contains a series of cutting-edge technological features of quality and innovation that make it unique in the oncological hyperthermia market. This equipment utilizes a highly complex TMS (Thermal Modulation System) protocol, which is technologically more advanced than standard Random Noise modulation.
22 Amplitude Modulations per hour of treatment.
Hybrid Frequency: Combines 13.56 MHz RF with pathology-specific frequencies.
ASK Modulation in OOK Mode
This mHT device generates high-intensity electromagnetic impulses programmed to persist over time using ASK (Amplitude-Shift Keying) in OOK (ON-OFF Keying) mode.
“We can send more power with impulses than in continuous mode; cancer cells cannot adapt as they do in continuous mode, while healthy cells can ‘wash out’ heat during the OFF cycles.”
This modality amplifies biological effects and offers the possibility of transmitting biological information to the tissues via a pathology-specific resonant effect.
Andromedic Advanced RF Modulation VS Other 13.56 MHz RF Hyperthermia Devices
Synergistic Biological Effects
- Vasodilation: Limiting the dissemination of malignant cells (ref).
- Deep Hyperthermia: Penetration up to 38.4 cm (superior to 8MHz cCHT) (ref).
- Joule Effect: Systematic increase in temperature of deep tissues (artificial fever).
- Gene Expression: Stimulation of therapeutic gene expression and variations in protein synthesis.
- Cellular Impact: Permeability variations and ionic displacement.
- Oxygenation: Significant changes in oxygenation of tumor and adjacent tissue.
- Immune Response: Release of cytokines and arrival of leukocytes; ICD (Immunogenic Cell Death) and TME modulation (ref).
- Drug Amplification: Resonance-specific amplification of drugs, pathogens (viruses/bacteria), and organelle targeting.
2025 Intelligent Software & Remote Management
The new software of the Andromedic HY-DEEP 600WM deep hyperthermia device offers 360° device management, designed to streamline clinical workflows and ensure patient-specific precision. It can be managed remotely via WIFI connection to a server or standalone PC, integrating seamlessly with electronic medical records.
- Data Recall: Instant access to patient therapy history, significantly speeding up preparation times.
- Automatic Mode: Power delivery (Watts) is automatically managed based on a matrix of pre-established values.
- Resource Optimization: Advanced automation leads to a notable reduction in professional resources required for treatment monitoring.
Personalized Treatment Protocols
The software features specific treatment protocols for each cancer type as well as for non-oncologic pathologies, which are not generic but dynamically adjusted based on:
Patient Height
Patient Weight
Distance between Electrodes
Andromedic HY-DEEP-600 WM
NEW LOOK 2025
Global Support & Remote Troubleshooting
An additional benefit of the 2025 software is the remote monitoring and diagnosis capability. Our experts at Andromedic’s headquarters can:
- Monitor mHT device performance in real-time.
- Perform remote troubleshooting in case of malfunctions of the mHT device.
- Provide distance assistance to ensure uninterrupted hyperthermia therapy sessions.
Once a problem occurs, we can see, diagnose, and fix it from a distance, minimizing downtime.
Precise Temperature Control
To ensure maximum safety and eliminate discomfort, the Andromedic HyDeep 600WM advanced oncologic hyperthermia device utilizes a sophisticated algorithm for calculating the indirect temperature of the treated area. This eliminates the need for invasive probes while preventing burns.
Safety Protocol:
Combined with real-time patient feedback, the system minimizes unwanted effects, ensuring they remain short-term and of minimal severity.
Biological Heat Management
Malignant Cells
Non-elastic vessels (simple epithelium) cannot expand. Heat is trapped, reaching 43°C for targeted apoptosis.
Non-elastic vessels (simple epithelium) cannot expand. Heat is trapped, reaching 43°C for targeted apoptosis.
Healthy Cells
Elastic vascularization allows “wash out” of excess heat. Maintains 38-39°C, creating a beneficial “Artificial Fever”.
Elastic vascularization allows “wash out” of excess heat. Maintains 38-39°C, creating a beneficial “Artificial Fever”.
This Targeted Hyperthermia for cancer ensures that while cancer cells are destroyed, healthy tissues are not only protected but also stimulated to activate the immune system through controlled thermal stress.
Patented Antennas & Electrode Technology
The patented electrodes used by the Andromedic HyDeep 600WM local hyperthermia device are engineered for both deep local penetration and superior patient safety. Featuring an integrated anti-burn cooling system, they ensure a high level of comfort throughout the session.
Unique Therapeutic Advantage:
“If a patient reports a burning sensation, you can reduce the electrode temperature (cool it down) without reducing the hyperthermia treatment power (Watts). This maintains maximum hyperthermia treatment efficiency while instantly restoring patient comfort.”
By shifting the focus of the RF through the combination of antennas, it is possible to treat superficial lesions with the same deep-local hyperthermia device.
Electrode Models & Cooling
Models: 270mm and 170mm (Flexible)
Cooling System: Water-based with adjustable temperature 2°C ÷ 30°C.
Elastic Positioning Bands
Sizes: 20 cm, 80 cm, and 120 cm
Antenna Spacers
Precision spacing for optimal energy delivery
Non-Invasive Cancer Treatment
Modulated RF-hyperthermia (mHT) is a purely non-invasive cancer therapy. It eliminates the risks associated with surgical interventions or invasive probes while delivering high-impact therapeutic energy deep into the body.
Potential Benefits of Hyperthermia for Cancer Patients:
- ✔
Improved Overall Survival (OS): Clinically significant increases in overall survival rates (ref). - ✔
Local Tumor Control: Effective stabilization and reduction of malignant masses. - ✔
Improved Quality of Life (QoL): Enhanced patient well-being, pain reduction, and palliative support.
*As demonstrated in multiple clinical trials, mHT provides a safe, effective, and patient-friendly addition to standard oncology protocols.
Clinical Demonstration
Watch the HY-Deep 600WM advanced oncologic hyperthermia device in a clinical setting. This video demonstrates the electrode positioning, the intuitive software interface, and the advanced 13.56 MHz technology in action.
All-In-One Hyperthermia Device
Therapeutic Excellence
-
- Deep selective controlled hyperthermia
- Electromagnetic effect synergy
vci
- Combined 13.56 MHz RF & Resonant Frequencies ( Pathology Specific RFs)
- Homogeneous heat diffusion
Mobility & Ergonomics
Lighter weight & easily moved: Featuring 4 industrial wheels. Move it effortlessly near the patient or between therapy rooms.
Operational Efficiency
Lower price & maintenance costs: We keep the service costs and acquisition price for our oncologic hyperthermia devices lower than our competitors. Contact us for details.
Interested in more information or a personalized quote?