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News :
Impact of Hyperthermia on Quality of Life (QoL): Pain Relief, Fatigue Reduction, and Adjuvant Immunological Benefits Hyperthermia and Survival of Cancer Patients: Clinical Evidence Demonstrating an Increase in Overall Survival (OS) by Over 50% Therapeutic Integration of Hyperthermia in Modern Oncology: A Critical Analysis of Phase III Trials and Meta-Analyses (OS, DFS, CR Endpoints) Quasi feasibility study(case control) associating deep local hyperthermia treatment with standard cancer treatments and describing patterns of response ESHO Preliminary results of chemoradiation plus hyperthermia and high dose rate brachytherapy for locally advanced cervical carcinoma ESHO
Andromedic HyDeep 600WM: Enhancing Modern Radiotherapy
A Clinical Review by Dr. Antonio Maria Costa (INI Grottaferrata)
Hyperthermia plays a critical role in the multidisciplinary attack on tumors. When associated with chemotherapy or radiation, it acts as a powerful catalyst for cell death. At the clinics of the INI Group, the innovative HyDeep 600WM Deep Local Hyperthermia device has become a fundamental part of the therapeutic path coordinated by Asl Roma.
Radiotherapy and Oncological Hyperthermia
Oncological Radiotherapy is a highly technological discipline, essential in the treatment of almost all neoplasms. Under the direction of Dr. Antonio Maria Costa, the INI Grottaferrata Center utilizes these technologies for:
Curative Purposes
Exclusive therapy replacing surgery for prostate or laryngeal cancer, or in association with surgery and chemotherapy.
Palliative Purposes
Powerful effect against pain and compression symptoms in metastatic patients, improving quality of life.
Modern Techniques at Grottaferrata
- 3D Conformal Radiotherapy: Precise anatomical targeting.
- IMRT (Intensity-Modulated RT): Irradiates complex shapes while saving nearby healthy organs.
- V-MAT (Volumetric Intensity-Modulated RT): Greater sparing of healthy tissues with increased execution speed.
- IGRT (Image-Guided RT): The latest frontier, allowing target volumes to be redefined during treatment for selective irradiation.
- Stereotactic Radiotherapy & Radiosurgery: High-dose radiation in limited sessions (1-5) to achieve immediate tumor necrosis.
State-of-the-Art Operational Unit
All treatments at INI Grottaferrata are supported by world-class infrastructure:
- Elekta “VERSA HD”: Integrated 4D cone beam CT & 6D HexaPOD robotic bed.
- Elekta “PRECISE”: High-reliability linear accelerator.
- Ray Station & Pinnacle: Advanced computerized treatment planning systems.
- ALIGN RT: Infrared, radiation-free patient positioning system.
Deep Oncological Hyperthermia with HyDeep 600WM
Hyperthermia involves the administration of heat (39-43°C) to tumor cells, causing irreversible damage and cell death.
The Biological Mechanism
The core advantage of hyperthermia lies in the vascular disparity between tissues. Tumor cells have an altered, inefficient vascular system, making them unable to dissipate heat. In contrast, healthy cells have efficient blood flow that easily eliminates excess heat, preventing side effects.
The HyDeep 600WM advanced oncologic hyperthermia device Advantage
The new 13.56 MHz radiofrequency device allows for deep and selective heating. Key benefits include:
- Synergy: Increases the effectiveness of Radiotherapy, Chemotherapy, and Immunotherapy without increasing toxicity.
- Protocol: A standard cycle includes 10 sessions (alternate days), lasting approx. 60 minutes.
- Patient Comfort: The treatment is absolutely painless. INI Grottaferrata provides a dedicated room where family members can stay during the procedure.
ALL RADIOTHERAPY AND HYPERTHERMIA SERVICES ARE PROVIDED BY THE SSN (Italian National Health Service) – PRIVATE – AND AGREED WITH MAIN INSURANCE COMPANIES.